Septic arthritis is a devastating disease requiring urgent surgical treatment and systemic antibiotics administration. As noted in the literature, degradation of cartilage occurs through cytokines, bacterial endotoxins, and other destructive enzymes invoking the host immune system [
1,
2]. This catastrophic cascade is likely to end with irreversible damage to the cartilage. Septic arthritis can even spread into the bone causing osteomyelitis. With recent advancements in arthroscopic techniques and devices, arthroscopic debridement and irrigation have become more popular and are regarded as the first-line treatment option rather than conventional open arthrotomy [
3,
4]. An arthroscopic approach provides better visualization of the joint and better preserves range of motion (ROM) and affected joint function as a minimally invasive approach. Several studies have reported satisfactory outcomes with arthroscopic debridement and irrigation [
1,
5,
6]. Nonetheless, the rate of reoperation after arthroscopic debridement remains as high as 26% to 32% [
1,
5,
6].
In “Arthroscopic treatment of septic arthritis of the shoulder: technical pearls to reduce the rate of reoperation” by Kwon et al. [
7], although there was no comment on the development of post-infectious arthritis in the affected shoulder, Jeon et al. [
5] described their clinical experience with 36 patients who underwent arthroscopic debridement for septic arthritis. They sought to provide technical tips in order to reduce the reoperation rate and to achieve satisfactory shoulder functional scores and ROM. Interestingly, just two patients underwent reoperation, which is a much lower recurrence rate than reported in previous studies addressing septic arthritis in the shoulder joint [
1,
5,
6]. The indications for reoperation in their study were: (1) failure of wound drainage output and C-reactive protein (CRP) level to decrease, or (2) evidence of persistent infection on postoperative magnetic resonance image (MRI).
On the other hand, Kim et al. [
1] reported that reoperation should be considered when (1) decreasing CRP level increases again, (2) a 7- to 10-day plateau in the decrease of the CRP level, or (3) failure of postoperative wound drainage output volume to decrease. The authors [
1] also suggested that persistent elevation of CRP should be an indication for reoperation. Although some authors proposed persistent pain with local warmth and limitation of motion or persistent infection on postoperative MRI as indications of reoperation, I do not think these measures are objective. Furthermore, it is difficult to differentiate resolution of infection from persistent infection on postoperative MRI. Even after the infection resolves and CRP returns to normal, soft tissue or synovium can be enhanced on gadolinium-enhanced MRI and this finding is non-specific [
5,
8]. Thus, CRP level can be an important and objective indicator for reoperation. Another objective indicator for reoperation can be wound drainage output volume failing to decrease [
1]. Aside from CRP level, I think that reoperation should be considered if wound drainage output does not decrease.
Lastly, one further question should be considered: should reoperation be performed as aggressive open arthrotomy? Although it may depend on surgeon preference, in the context of significant bone lesions present at advanced stages, I think an open arthrotomy would be better rather arthroscopic approach. Kwon et al. [
7] indicated that to reduce the reoperation rate in septic arthritis, the use of a posterolateral portal, a 70° scope in the subacromial space, a large volume of irrigation (>20 L), and multiple suction drains after surgery are recommended.